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ProstT5

Rostlab · ProstT5

ProstT5 is a protein language model (pLM) which can translate between protein sequence and structure. ProstT5 (Protein structure-sequence T5) is based on ProtT5-XL-U50, a T5 model trained on encoding protein sequences using span corruption applied on billions of protein sequences. ProstT5 finetunes ProtT5-XL-U50 on translating between protein sequence and structure using 17M proteins with high-quality 3D structure predictions from the AlphaFoldDB. Protein structure is converted from 3D to 1D using the 3Di-tokens introduced by Foldseek. In a first step, ProstT5 learnt to represent the newly introduced 3Di-tokens by continuing the original span-denoising objective applied on 3Di- and amino acid- (AA) sequences. Only in a second step, ProstT5 was trained on translating between the two modalities. The direction of the translation is indicated by two special tokens ("\ " for translating from 3Di to AAs, “\ ” for translating from AAs to 3Di). To avoid clashes with AA tokens, 3Di-tokens were cast to lower-case (alphabets are identical otherwise). - **Developed by:** Michael Heinzinger (GitHub @mheinzinger; Twitter @HeinzingerM) - **Model type:** Encoder-decoder (T5) - **Language(s) (NLP):** Protein sequence and structure - **License:** MIT - **Finetuned from model:** ProtT5-XL-U50

译文排队中,当前展示来源原文。

语言翻译license:mit
上下文窗口来源未披露
输入 → 输出文本 → 文本
模型权重待核验
档案更新时间2026/10/31 15:23:30
OVERVIEW

模型介绍

ProstT5 is a protein language model (pLM) which can translate between protein sequence and structure. ProstT5 (Protein structure-sequence T5) is based on ProtT5-XL-U50, a T5 model trained on encoding protein sequences using span corruption applied on billions of protein sequences. ProstT5 finetunes ProtT5-XL-U50 on translating between protein sequence and structure using 17M proteins with high-quality 3D structure predictions from the AlphaFoldDB. Protein structure is converted from 3D to 1D using the 3Di-tokens introduced by Foldseek. In a first step, ProstT5 learnt to represent the newly introduced 3Di-tokens by continuing the original span-denoising objective applied on 3Di- and amino acid- (AA) sequences. Only in a second step, ProstT5 was trained on translating between the two modalities. The direction of the translation is indicated by two special tokens ("\ " for translating from 3Di to AAs, “\ ” for translating from AAs to 3Di). To avoid clashes with AA tokens, 3Di-tokens were cast to lower-case (alphabets are identical otherwise). - **Developed by:** Michael Heinzinger (GitHub @mheinzinger; Twitter @HeinzingerM) - **Model type:** Encoder-decoder (T5) - **Language(s) (NLP):** Protein sequence and structure - **License:** MIT - **Finetuned from model:** ProtT5-XL-U50

主要特点

特点摘要待依据来源补齐,不凭模型名称推断能力。

局限与注意事项

暂无足够来源支持具体缺点结论。请重点验证实际任务表现、时延、数据政策、许可与版本生命周期。

PRICING & COST

来源报价与费用分析

同一模型在不同渠道、地区和配置下可能采用不同价格。下表独立保留各渠道报价,不将渠道价格视为厂商官方统一价格。

来源 / 渠道输入输出计费单位采集时间
暂未取得可核验报价,请查阅来源渠道。

按月估算基础 Token 费用

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预估不包含缓存优惠、阶梯定价、多模态附加费用、网络检索、税费及推理额外输出。

INDEPENDENT BENCHMARKS

公开评测与运行配置

暂无已采集的可核验公开评分。模型未上榜不代表能力较低。

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常见问题

开放权重是否代表可以免费商用?

不一定。应核对具体版本许可证、商用门槛和使用政策。自部署还会产生算力和维护成本。

这些价格是实时结算价格吗?

不是实时结算价格,而是带采集时间的来源报价快照。请到对应渠道核对当前版本、区域、折扣和计费方式。

资料来源与可追溯记录

许可证:mit。模型介绍与第三方评测均以原来源的具体版本和方法为准。