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How Indegene is modernizing and scaling enterprise data quality in life sciences

This post explores how Indegene built a production-grade, LLM-powered Data Quality Agent in its NEXT Unified Data Platform on AWS. The agent generates context-aware data quality rules, validates them, and produces ready-to-run SQL and Python under human-in-the-loop governance, helping life sciences organizations scale enterprise data quality.

How U Mobile built agentic telco operations with Amazon Bedrock AgentCore

U Mobile, Malaysia's newest 5G network provider, built AiDaH, an agentic AI operations platform on Amazon Bedrock AgentCore that moves beyond AI assistance to autonomous action across telco operations. Nine months after production launch, AiDaH handles over 150 operational scenarios across six divisions, cutting trouble tickets by up to 84.5%.

A thousand fewer paths to root

OpenAI built an autonomous pipeline that found, validated, and generated patches for 948 local privilege-escalation vulnerabilities in the Linux kernel.

Predictive gains, causal losses: why interventional competence cannot be learned from data alone

arXiv:2611.03861v1 Announce Type: new Abstract: Retaining predictive gains can require persistent errors in a model's response to interventions. For deterministic predictors with finite second moments under squared-error loss, any observational advantage over the best predictor using only an outcome's direct causes requires dependence on other inputs, regardless of the learning rule. When admissible interventions vary inputs while preserving the worldly outcome, this dependence yields a positive lower bound on root-mean-square intervention-response error. We identify conditions under which population gradient updates introduce this dependence from a parent-only baseline or damage a previously correct mechanism through shared parameters while improving other predictions. These dependencies can also make model behavior vary with how the same intervention is realized. We characterize interventional alignment through a common output mapping across internal states and physical processes realizing the same intervention target and relevant context. Correction is limited by the causal hypotheses currently admitted within inquiry. The relevant hypothesis class comprises these causal alternatives, rather than the function class the computational system could in principle represent. For predictions restricted to these alternatives, interventional mean error cannot fall below the best approximation they permit, whether evidence is observational or interventional. Reducing error below a positive limit requires admitting better hypotheses, which may entail revising the causal variables, mechanism structure, or intervention interpretation. Interventional criticism constrains replacements without determining them. We conjecture that reliably acquiring and maintaining interventional competence when causal commitments fail requires autonomous participation in proposing alternatives, testing their consequences, and revising them in response to error.

Towards Automatic Heart Murmur Characterization from Multi-spot Phonocardiograms

arXiv:2611.03654v1 Announce Type: new Abstract: Cardiac auscultation traditionally detects the presence of a heart murmur, but clinicians further characterize it by timing, shape, pitch, quality, and grade. Most automatic phonocardiogram analysis systems stop at binary detection and do not estimate this richer description. In this work, we formulate automatic murmur characterization as five patient-level classification tasks and compare three multi-spot strategies on recordings from the aortic, pulmonary, mitral, and tricuspid auscultation locations. First, classical and deep-learning classifiers are trained independently at each location, and predictions are combined via a maximum-severity late-fusion rule. Second, a synchronous multi-input CNN jointly processes one representative segment per location for a single task. Third, a unified multi-input, multi-output CNN predicts all five attributes from one shared multi-spot representation. Using 735 patients from the CirCor DigiScope dataset with complete four-spot recordings, the best late-fusion configurations reach an unweighted mean sensitivity between 85.56% and 93.81% across the five tasks, with class-specific recalls between 80.00% and 100.00% for every relevant category. The multi-input CNN trails late fusion by 7-16 points depending on the task, while the multi-output model reaches values between 72.59% and 79.40%, estimating all five attributes from one shared representation. We further show that naively balancing training data by adding all minority-class segments degrades patient-level performance under the maximum-severity rule, since it introduces non-representative, noisy segments not filtered by the clustering-based segment selection used for evaluation. These results indicate multi-spot murmur characterization is feasible with both fusion-based and jointly learned architectures, outlining a path toward automatic, structured murmur reports complementing binary screening.

v1.19.0 - Trace Your Workflows, Layer by Layer

Dify 1.19.0 enhances observability with nested workflow tracing, allowing users to follow execution steps inside Workflow Tools, inspect LLM calls, and maintain context across nested invocations. The release also enables portable app packages via App packages, improves Agent file uploads and previews, introduces Skill Hub automation through CLI commands, and upgrades the bundled plugin daemon to version 0.6.14-local. Key changes include support for format v2 app packages, enhanced security, improved editing workflows, and updated environment variables and API endpoints.

Wabi reels in $55M for its consumer-focused AI assistant

Wabi Inc., the developer of an artificial intelligence assistant for consumers, today announced that it has raised $55 million in funding. IVP led the seed round with contributions from Amazon Alexa Fund, Andreessen Horowitz and Forerunner. They were joined by a group of angel investors that included Salesforce Inc. CEO Marc Benioff and Shopify Inc. […] The post Wabi reels in $55M for its consumer-focused AI assistant appeared first on SiliconANGLE.

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b11954

tests : adjust constants to reduce irrelevant warnings (#31254) **Website:** - **Attestations:** - **macOS/iOS:** - [macOS Apple Silicon (arm64)](https://github.com/ggml-org/llama.cpp/releases/download/b11954/llama-b11954-bin-macos-arm64.tar.gz) - macOS Apple Silicon (arm64, KleidiAI enabled) [DISABLED](https://github.com/ggml-org/llama.cpp/pull/23780) - [macOS Intel (x64)](https://github.com/ggml-org/llama.cpp/releases/download/b11954/llama-b11954-bin-macos-x64.tar.gz) - [iOS XCFramework](https://github.com/ggml-org/llama.cpp/releases/download/b11954/llama-b11954-xcframework.zip) **Linux:** - [Ubuntu x64 (CPU)](https://github.com/ggml-org/llama.cpp/releases/download/b11954/llama-b11954-bin-ubuntu-x64.tar.gz) - [Ubuntu arm64 (CPU)](https://github.com/ggml-org/llama.cpp/releases/download/b1

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Benchmarking Task Takeover Across Agent Handoffs

arXiv:2610.36523v1 Announce Type: new Abstract: As agents collaborate on longer tasks, responsibility may pass between models before the work is complete. The receiving model must build on prior decisions, observations, and actions while addressing the remaining requirements. Evaluating this transition requires connecting the information preserved at handoff to how the receiver continues the work, a relationship that task-success and memory-retention scores alone do not capture. We introduce the Handoff State Continuity Benchmark (HSC-Bench), comprising 1,039 tasks that evaluate two complementary aspects of task takeover: recovering relevant repository evidence and continuing from established conversational, tool, and file-work state. Comparisons across six receiving models show that struc

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