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A Night at the LLM Zoo: Data Conditioned Flow Matching for Generating Pretrained LLM Weights

arXiv:2611.07103v1 Announce Type: new Abstract: A challenge to Weight Space Learning as it expands from task specific and vision models to Large Language Models (LLMs) is the absence of a well curated and analyzed LLM population. To address this, we train such a model zoo for application to Weight Space Generation by systematically varying the data mixture composition between web text, books, mathematics, coding, and French across populations of 51M, 124M, and 355M parameter GPT-2 Models, each tier with count N = 100. We analyze these populations by cosine similarity, functional diversity, Leave-One-Mixture-Out modeling, and variance decomposition. We show that the zoo contains diverse models whose variation is structured by training mixture composition. We embed the training mixture composition to condition a Flow Matching model of complete pretrained LLM weights in Gram-PCA compressed weight space. By demonstrating zero-shot generalization to held out mixtures, measuring Continuous Ranked Probability Score skill, as well as finding minimal changes in downstream test-set perplexity and general capability benchmark scores, we show that our generator generalizes on the simplex of data mixtures to produce models that perform similarly to those in the zoo ex nihilo. Finally, we produce all source code and artifacts to support the continued expansion of Weight Space Learning and Generation into the LLM domain.

KDASO: Knowledge-Data Dual-Driven Automated Skill Optimization for Liability Adjudication Tasks

arXiv:2611.06972v1 Announce Type: new Abstract: Liability adjudication tasks (e.g., legal charge determination) require analyzing event descriptions against domain-specific skills to determine whether a party should bear liability. While Large Language Models (LLMs) have shown promise in this area by leveraging executable skills for interpretable reasoning, existing approaches face three critical limitations: skill libraries become stale as real-world scenarios dynamically evolve, skill descriptions often suffer from a semantic execution gap where LLMs deviate from intended expert logic, and growing skill collections exceed context budgets causing critical skill omission. To address these challenges, we propose Knowledge-Data Dual-Driven Automated Skill Optimization (KDASO), which continuously evolves a skill library through neighborhood-conditioned induction from recent adjudication data, execution-aligned refinement based on LLM trajectory analysis, and context-budgeted routing for scalable skill selection. Experiments across ride-hailing adjudication, legal liability determination, and logical reasoning judgment demonstrate that KDASO significantly outperforms current general-purpose and domain-specific baselines. KDASO further achieves 8.96% improvement when transferring skills to concept-similar scenarios and maintains consistent performance gains through continuous optimization, underscoring the high transferability and stability of generated skills.

NUMA-Torch: Compiler-Driven NUMA-Aware LLM Prefill on Multi-Socket CPUs

arXiv:2611.07105v1 Announce Type: new Abstract: For sufficiently large transformer-based Large Language Models (LLMs), whose parameters cannot be retained in on-chip caches, prefill throughput on multi-socket CPUs is often limited by sustainable DRAM bandwidth rather than peak floating-point throughput. In the standard PyTorch compilation (i.e., TorchInductor) path, model weights are allocated without considering the Non-Uniform Memory Access (NUMA) topology: specifically, the affinity between memory banks and compute cores is disregarded. This causes a substantial fraction of weight accesses to traverse the inter-socket interconnect, severely degrading the effective memory bandwidth available to each socket. We address this bottleneck through a compiler-level solution that makes TorchInductor NUMA-aware. Treating each NUMA socket as an independent tensor-parallel partition, we introduce NUMA-aware Tensor Parallelism (NUMA-TP). This approach transparently shards weights across sockets and schedules compute kernels such that thread pools and memory allocations remain strictly local to their respective sockets using CPU affinity. We evaluate the approach on GPT-2 (117M, 345M, 762M) and BERT (Small, Large), which exercise standard multi-head attention and MLP, as well as Gemma 3 270M, which combines Multi-Query Attention with a GeGLU-gated MLP. By strictly enforcing data locality, our approach successfully mitigates cross-socket traffic, achieving prefill speedups of up to 2.63x on a dual-socket Haswell platform, up to 1.87x on a dual-socket Cascade Lake platform, and up to 2.27x on a four-socket Haswell-EX platform.

ProcessPrefBench: Evaluating Cross-Task Transfer of Individual Process Preferences from Naturalistic Human-AI Interaction

arXiv:2611.06065v1 Announce Type: new Abstract: In natural human-AI dialogue, users' corrections, requests, and self-descriptions carry reusable signals about how they want work to be done. These signals reveal individual process preferences, user-specific standards for evidence, depth, analytical focus, procedure, and delivery. We ask whether a preference revealed in one dialogue can shape an assistant's later answer when the task does not restate it. ProcessPrefBench uses three months of natural dialogues from two knowledge workers to build 66 source-target cases separately judged for source evidence and target applicability. Sources are preselected, so the benchmark tests application rather than retrieval. We test three models with target-only, full-history, and distilled-preference prompts. Target-specific 0-2 rubrics score preference realization, and a task gate flags severe failures. Compared with target-only prompting, full-history and imperative distilled-preference prompting raise preference realization by 0.204 and 0.244 points on the 0-2 scale, respectively, with no reliable advantage from distillation. Fabricated-evidence failures rise from 5.8% under target-only prompting to 10.1% under full-history and 10.4% under imperative prompting. ProcessPrefBench highlights a tension in learning from dialogue, where drawing on prior interactions can improve preference realization yet also invite fabricated evidence. We hope it helps build assistants that honor a user's process preferences without sacrificing factual reliability.

The Two-Ledger Model: Transaction-Grain Cost Accounting for Multi-Agent AI Systems Across Clouds, Models, and Systems of Record

arXiv:2611.06989v1 Announce Type: new Abstract: Enterprises run business transactions through multi-agent AI systems spanning clouds, large language models (LLMs), orchestration harnesses, and systems of record. Finance receives AI cost only at settlement grain, aggregated by SKU and charge period. The business question (what did this order, claim, or case cost in AI?) cannot be answered from billing data, because providers never see enterprise transaction boundaries. The FinOps Open Cost and Usage Specification (FOCUS) gives billing data one schema across providers but remains settlement-grain even as it adds AI token and requester attribution. We formalize this grain mismatch, derive seven requirements, and propose the Two-Ledger Model: a settlement ledger of FOCUS-conformant billing data joined to an attribution ledger of invocation-grain usage records built on OpenTelemetry GenAI telemetry. A layered correlation spine (trace context, A2A/MCP metadata, business-key correlation, probabilistic matching) assigns each record to its business transaction with recorded method and confidence; a versioned rate card prices usage in near real time; period reconciliation ties both ledgers to the invoice, and the unexplained residual identifies shadow AI. Costs are reported per order, claim, or outcome with agentic cost metrics. A simulation with known ground truth shows the spine sustaining cost coverage above 99% as trace propagation falls to zero, the reconciliation residual recovering planted unmetered spend within 0.24 percentage points while flagging provider billing errors, and mid-flight gating cutting p99 transaction cost by up to 61% at a 2-4% false-pause rate. We propose the attribution ledger as an invocation-grain FOCUS profile for standardization.

Uncertainty calibration in Bayesian M/EEG source imaging

arXiv:2611.06979v1 Announce Type: new Abstract: M/EEG source imaging requires accurate localization and reliable uncertainty estimates, yet posterior credible regions are rarely assessed for empirical calibration. We present a simulation-based framework for uncertainty quantification and calibration of empirical Bayesian inverse methods with closed-form conditional Gaussian posterior summaries. We compare Bayesian minimum norm (BMN) with sLORETA depth weighting and sparse Bayesian learning (SBL) with sparse basis field expansions (S-FLEX). S-FLEX allows retained coefficients to contribute nonzero marginal posterior variance at locations where voxel-wise SBL yields degenerate variances. For BMN, we derive joint source- and noise-variance updates through evidence maximization. We test whether adaptive noise learning yields near-calibrated uncertainties. Both methods retain residual miscalibration, motivating post-hoc isotonic recalibration of credible-region levels using empirical coverage. Simulations assess fixed- and free-orientation models across signal-to-noise ratios (SNR), source sparsity levels, and subject-specific head models, using oracle, baseline-estimated, and adaptively learned noise. Before recalibration, SBL+S-FLEX yields lower Wasserstein localization error, smaller posterior uncertainty, and coverage closer to nominal credibility than BMN+sLORETA. Isotonic recalibration improves both methods, with larger gains for conservative BMN+sLORETA posteriors; transfer across mismatched SNR, sparsity, and head models remains condition dependent. Noise specifications yield broadly consistent reconstruction and uncertainty trends within each estimator. In real auditory MEG data, SBL+S-FLEX provides more focal localization and tighter uncertainties than BMN+sLORETA, suggesting greater statistical power for identifying bilateral auditory sources.

Assurance-Conditioned Continuous Authorization for Autonomous AI Agents

arXiv:2611.05632v1 Announce Type: new Abstract: Autonomous software agents can act through tools, delegate work, and change their models or execution environments while earlier authorizations remain in flight. We present Assurance-Conditioned Continuous Authorization (ACCA), an approach designed to be harness-independent, for maintaining operational authority according to currently justified assurance. It distinguishes evidence validity from contextual applicability, derives assurance claims from eligible evidence, and resolves a multidimensional effective-authority envelope within a principal-declared ceiling and applicable policy. A typed dependency graph supports selective re-evaluation of authorization-relevant changes. An authority epoch changes when effective authority changes; a distinct optional authorization-basis version supports revalidation of action-specific authorization conditions. Protected effect-time enforcement can reject stale actions before a consequential resource change, subject to the available commit mechanism. A compositional Domain Governance Profile expresses domain-specific semantics without granting authority. Controlled scenario tests implemented as a regression suite using a trading profile exercise default-deny rules, evidence-conditioned contraction and recovery, policy divergence, selective non-response, and stale-action rejection at a local gateway before the simulated-broker boundary. The study establishes implementation-level evidence in one domain, not a cross-domain guarantee of harmful-behavior prevention.

Stacking-Based Weighting for Large Language Bayes in M-Open Settings

arXiv:2611.03966v1 Announce Type: new Abstract: Large Language Bayes (LLB) transforms a natural language problem description into a collection of candidate probabilistic programs and performs inference within each model, combining their predictions using Bayesian model averaging. While this provides a flexible framework for probabilistic inference without manual model specification, the resulting candidate model set is often misspecified in practice, and likelihood-based aggregation can concentrate on a single model, under-representing uncertainty across the sampled models. We propose a stacking-based aggregation method for LLB that selects model weights by optimizing predictive performance rather than marginal likelihood, while preserving the original language-model-driven model generation and within-model inference pipeline. Because leave-one-out predictive quantities are intractable in latent-variable models, we derive a variational lower bound that yields a tractable ELBO-based stacking objective. Across real-world probabilistic inference tasks, our method achieves comparable predictive performance to Bayesian model averaging while yielding more dispersed model weights, reducing concentration on a single candidate model under misspecification.

Verified but Vacuous: Three Failure Surfaces of LLM-Driven Verified Code Generation

arXiv:2611.05590v1 Announce Type: new Abstract: What should ``verified'' mean when evaluating LLM-generated code? Many existing pipelines report a single verification number. We argue this collapses three distinct properties measured in a conditional audit sequence: verifier acceptance (Surface A), \emph{syntactic specification binding (Surface B: does the proof obligation bind to the spec?), and \emph{semantic specification fidelity} (Surface C: does the spec capture the informal requirement?). Two empirical demonstrations show the surfaces separate. \textbf{First ($A \neq B$), via Li@Opus (a same-model reproduction of \citet{li2025dafny}'s Dafny-as-intermediate-representation (IR) pipeline under Claude Opus 4.7) on three Python benchmarks}: it reaches \textbf{99.1\% verifier acceptance} on HumanEval while only \textbf{1.9\%} carry a certificate binding to a spec-defined predicate or function. \textbf{Second ($B \neq C$), via VCG on two Rust benchmarks}: we use VCG (which is our own in-house Dafny-as-intermediate pipeline) on Rust because the Rust target lets us enforce fully-verifiable output (every component ships as a Dafny certificate, ensures-binding gate passing by construction). Even inside that construction, \textbf{11.48\% (MBPP-Rust) and 14.82\% (VeriContest LC slice) of structurally-verified samples still fail hidden tests}. On the LC slice of VeriContest, \textbf{VCG's reported End2End rate is 7.79\% (535/6870).} The cited external rates are 5.51\% (GPT-5.5) and 1.88\% (single-shot Opus 4.7). These give descriptive differences of 2.3 percentage points and 4.14$\times$, respectively; task-budget, repair and harness differences prevent a matched-performance claim.

VirtualTrialHarness: Coordinating Agentic Operationalization of Virtual Trial Protocols Across Complex Clinical Schemas

arXiv:2611.05551v1 Announce Type: new Abstract: Virtual trials use routinely collected clinical data to evaluate treatment strategies, but translating a study protocol into an executable analysis requires determining how clinical concepts and study requirements should be represented in the available data and applied consistently across the workflow. These decisions depend on local data representations and operational conventions and can involve source selection, patient and encounter identity, linkage, and temporal interpretation. Here we introduce VirtualTrialHarness (VTHarness), an agent framework that coordinates virtual-trial operationalization by selecting reusable procedural skills for each workflow stage and uses explicit contracts to maintain consistent study decisions across stages. We also introduce VTBenchmark for evaluating source selection and cohort construction. Across three complex synthetic environments, VTHarness successfully produced all required cohort outputs matching the references in 95.1% of workflows after requirement clarification, compared with 60.4% using retrieval from the same procedural corpus. Procedural skills improved source recovery across three language models and increased source overlap with analyst code in 13 Mayo Clinic cases. Site-specific adaptation enabled reference-matched cohort execution across eight MIMIC-IV tasks. Within the Mayo Clinic Virtual Trials Program, the framework supported investigator review of cohort construction and endpoint analysis. These findings support coordinating procedural guidance with workflow decisions to improve virtual-trial implementation across complex clinical schemas.

CaRe-KT: Continuity-Aware Retrieval-Augmented Reasoning for Knowledge Tracing

arXiv:2611.03744v1 Announce Type: new Abstract: Knowledge tracing (KT) estimates learners' evolving knowledge states from interaction histories to support adaptive learning. Retrieval-augmented KT improves these estimates using cross-learner behavioral evidence, but existing approaches typically separate evidence retrieval from downstream prediction. This creates a retrieval-inference alignment gap because evidence relevance varies with the learner's evolving state and prediction context. We propose CaRe-KT, a query-adaptive framework that maintains relevance continuity between evidence acquisition and inference without equating retrieval relevance with predictive utility. CaRe-KT introduces an Evidence-Graph Cache (EGC) that combines persistent question-level relational compatibility with interaction-level temporal validity to construct query-specific evidence subgraphs. Historical learning trajectories retrieved through these subgraphs are encoded alongside the target learner's history in a shared representation space using outcome-supervised contrastive learning. An attention mechanism combines acquisition relevance with learned query-evidence compatibility, allowing relevance to inform, rather than determine, each trajectory's predictive influence. Experiments across five benchmarks show that CaRe-KT outperforms strong KT baselines and remains robust under sparse-history and cold-start conditions. These findings support relevance continuity as a design principle for retrieval-augmented knowledge tracing.

Co-Occurrence Priors Override Visual Spatial Evidence: Understanding False Alarms in Vision-Language Models for Construction Struck-By Hazard Detection

arXiv:2611.04112v1 Announce Type: new Abstract: Vision-language models (VLMs) increasingly support construction hazard monitoring, yet their frequent false alarms remain poorly understood. This study investigates whether false struck-by hazard warnings arise from failures in object recognition, spatial relation encoding, or hazard decisions dominated by learned co-occurrence priors. We evaluated Qwen2.5-VL-7B and InternVL3.5-8B using 355 counterfactual worker-excavator scene pairs with controlled spatial proximity and worker-removal variants, combining behavioral analysis, internal representation probing, causal interventions, and decision correction. Both models recognized the entities and encoded their spatial relations (out-of-fold AUROC: 0.82 and 0.91), assigning higher hazard scores to near than far scenes in 79% and 73% of pairs. Nevertheless, 74% and 100% of far scenes were falsely classified as hazardous. Removing the worker reduced Qwen's hazard rate to 11%, while worker presence exerted 2.4- and 3.2-times greater influence on hazard scores than spatial proximity in the respective models. Attention-head interventions, neuron-level interventions, and activation steering failed to eliminate this co-occurrence bias. However, conditioning hazard decisions on the model's own spatial-relation representation improved Qwen's specificity from 0.36 to 0.58 at matched sensitivity, outperforming threshold recalibration. These findings reveal that VLM struck-by false alarms stem primarily from decision-making failures rather than deficiencies in object recognition or spatial encoding, suggesting that future efforts should prioritize conditioning hazard decisions on encoded spatial evidence rather than further improving visual recognition alone.

Do Pretrained Backbones Transfer to Physical Sensors? A Systematic Study of Multimodal Initialization Across the Sensor Stack

arXiv:2611.04034v1 Announce Type: new Abstract: Transfer learning from pretrained backbones has become standard practice in multi-sensor computer vision---yet two questions remain open: which pretrained weights transfer best to multi-sensor setups, and can in-domain pretraining outperform off-the-shelf solutions? Frameworks like MultiMAE demonstrate the utility of masked autoencoding in a multi-modal context, but rely entirely on dense, model-derived modalities. It is unclear how robustly these methods translate to real-world applications that use physical sensors, where the aggregation of diverse public datasets for large-scale pretraining inherently introduces modality sparsity. To investigate this systematically, we curate a multi-sensor autonomous driving collection of $2.82M$ images from 16 publicly available datasets, incorporating both physical hardware modalities (RGB, LWIR, NIR, Event) and model-derived modalities (Stereo Depth, Segmentation). We use this collection for in-domain pretraining based on the MultiMAE approach. We adapt MultiMAE's loss formulation to accommodate sparse samples, and study the effect of an enforced encoder bottleneck for modality alignment and of additional losses specific to dense reconstruction (SSIM and FFT). We then systematically compare against common pretrained backbones (ViT, MAE, DINO and MultiMAE) across downstream sensor fusion tasks. We find that MultiMAE is a surprisingly strong out-of-the-box baseline, transferring effectively even to modalities it has never seen, while our targeted modifications yield incremental but consistent improvements on multi-sensor transfer and overall robustness.

Do We Still Need Rotation-Invariant Architectures? A Statistical Robustness Benchmark for Point Cloud Classification

arXiv:2611.03952v1 Announce Type: new Abstract: A substantial line of work builds rotation invariance directly into point cloud architectures. We benchmark 10 architectures (PointNet, PointNet++, DGCNN, RIConv, RIConv++, RISurConv, PointMLP, PointTransformer, and the equivariant VN-PointNet and VN-DGCNN) across 5 domains under pose, noise, and occlusion, and analyze the results with confirmatory hypothesis tests rather than point estimates. The three rotation-invariant (RI) architectures achieve the best pose robustness but rank among the lowest on noise robustness in 4 of 5 domains. We ask whether this cost is intrinsic to invariance or specific to how invariance is obtained. We retrain all 10 architectures unchanged, with a simple invariance loss on the embedding and three training seeds each, and evaluate all models on the independently designed ModelNet40-C. Invariance training transfers narrowly but reliably. It improves exactly the corruption families its perturbations target wherever the baseline has headroom (mean occlusion +10.5, lidar +13.4 percentage points of accuracy). At matched training budget the best standard backbone and the best RI architecture end on par on unseen corruptions (within 2.5 percentage points in every seed), and invariance-trained RIConv++ is the most seed-stable top model. Once rotation augmentation is widened, standard backbones concede only a flat, angle-independent accuracy offset under full-sphere rotation. We release the benchmark along with a package for analyzing point cloud robustness and reproducing our results.

LOLPlay: Benchmarking Real-Time Visual Agents in League of Legends

arXiv:2611.03685v1 Announce Type: new Abstract: Visual agents need to coordinate reasoning and action while their environment evolves during inference. We introduce LOLPlay, a benchmark in native \emph{League of Legends} with 36 champion-specific tasks spanning resource management, combat, cooperation, and objectives. Agents interact through screenshots and mouse--keyboard actions; automated initialization and 82 executable subgoal checks distinguish partial progress from completion. Across 324 task evaluations of three models at three reasoning-effort settings, GPT-6 Astra achieves the highest task success rate of 25.0\% at low and medium effort, and the highest subgoal success rate of 40.3\% at medium effort. However, high effort improves neither metric over low effort for any model. For Astra, longer requests leave fewer interaction rounds, suggesting a cost to additional reasoning in real-time control. Trajectories reveal incomplete subgoal composition and actions executing after the observed scene changes, motivating agents that combine visual reasoning with timely action.

MCPGuard: Finding Conformance Gaps in MCP SDKs via Dual-Track Analysis and Dynamic Adjudication

arXiv:2611.03662v1 Announce Type: new Abstract: The Model Context Protocol (MCP) connects large language model agents to external tools and services through official SDKs that implement message validation and session logic. Specification constraints omitted by these SDKs may propagate to downstream applications, highlighting the importance of SDK-level conformance testing. Yet existing MCP conformance tools mainly exercise running endpoints and reveal little about whether SDK models enforce specification requirements. We present MCPGuard, an automated LLM-based framework for detecting specification-to-SDK conformance gaps. Its structural track aligns JSON Schema constraints with normalized SDK models and produces constraint-specific evidence. Its behavioral track extracts normative prose rules, retrieves bounded function-level slices, and audits them with LLMs for candidate omissions. An evidence-aware dynamic adjudicator then inspects complete source context and builds PoCs to validate candidates. A shared kernel with language-specific adapters enables analysis across SDKs. On the official Python 1.26.0 and TypeScript 1.29.0 SDKs, MCPGuard confirms 13 and 19 findings, respectively, none of which are exposed by two black-box baselines. Tests on open MCP servers further show that these gaps can systematically propagate downstream. By making SDK conformance of specification constraints directly testable, MCPGuard complements conventional endpoint-oriented conformance suites.

Minimal Superior Penalties: Characterising and Calibrating Decision-Aware Proper Scoring Rules

arXiv:2611.03734v1 Announce Type: new Abstract: Training a classifier means letting a validation metric decide which model is kept and when training stops. A natural requirement on that metric is superiority: every correctly classified forecast should score better than every incorrectly classified one, however close the underlying probabilities are. Neither the Brier score nor the logarithmic score satisfies this on its own. We show that superiority is governed by the separation between two endpoints -- the supremum of the score on correct predictions and the infimum on incorrect predictions -- and derive both in closed form for each score. Their difference is the infimal penalty, the greatest lower bound on the penalty needed to restore superiority. Prior work restores superiority with a penalty calibrated from the first endpoint alone; for the Brier base, our infimal penalty is smaller than that published penalty by a factor ranging from 4.00 at three classes to 2.11 at twenty. We further embed the published and infimal penalties in a one-parameter family and show that, under a single-valued tie convention, every member of the family is strictly proper. In a pre-specified two-dataset case study, mean selected-model macro-F1 rises with the penalty in the reported ten-class regimes, though not distinguishably from noise once seed/selection-mode nesting is accounted for; a fifth regime at forty-seven classes does not reproduce even this descriptive pattern. The intended no-superiority baseline is algebraically a rescaling of the family under test, so the experiment cannot attribute the observed pattern specifically to superiority. When superiority itself is the objective, any penalty strictly above the infimal value suffices; choosing a larger penalty is a separate calibration trade-off rather than a requirement for the guarantee.

Rethinking Next-Visit Diagnosis Prediction Beyond Aggregate Metrics: Retrieval--Memory Multi-Agent Adjudication

arXiv:2611.03826v1 Announce Type: new Abstract: Next-visit diagnosis prediction forecasts the diagnoses documented at a patient's next encounter, turning retrospective electronic health records into prospective clinical prediction. However, conventional aggregate evaluation obscures its multifaceted nature: distributionally, models must handle variable-size diagnosis sets and long-tailed labels; temporally, they must distinguish persistent, newly recorded, and recurrent diagnoses; and both vary with observed history depth. We introduce an evaluation framework along these dimensions and apply it to rule-based heuristics, LLM-based prompting, retrieval, memory, and multi-agent approaches. This reveals that repeating the last visit outperforms most LLM-based approaches overall despite predicting no new or recurrent diagnoses, and that retrieval and memory exhibit distinct profiles whose relative strengths vary across temporal transitions and backbones. Motivated by this, we propose LONGINUS, a retrieval-memory multi-agent adjudication framework combining evidence retrieved from patient records with structured memory of the patient trajectory. Using cross-view agreement as a reliability heuristic, it preserves shared predictions and adjudicates disagreements without revealing their source. Across MIMIC-III and MIMIC-IV with four LLM backbones, LONGINUS achieves the best transition-specific performance among LLM-based methods in nearly all settings while remaining competitive with them on aggregate metrics.

ScienceVision: Can AI Observe and Reason Like a Scientist?

arXiv:2611.04087v1 Announce Type: new Abstract: Scientific discovery builds on accurate observations interpreted through domain knowledge and reasoning. For scientific 3D data, this requires understanding structures and spatial relationships, from protein contacts to anatomical organization. Existing multimodal benchmarks largely evaluate text and 2D images, while scientific 3D evaluations vary in representations and protocols across disciplines, limiting cross-disciplinary comparison. To assess these foundational capabilities, we introduce ScienceVision, a cross-domain benchmark for scientific 3D understanding and reasoning through expert-level visual question answering (VQA). We construct 250 questions, with 50 each from Biology, Chemistry, Medical Imaging, Mechanical CAD, and Architecture, through a pipeline combining synthetic question generation with domain-expert review and annotation. Each task pairs a native 3D artifact with a scientific question, a specified response format, and a task-specific reference answer, requiring domain knowledge to be applied to geometric or topological evidence. We evaluate 12 models on the same questions in three settings: visual question answering with native 3D artifacts accessed through an agent harness's file and code-execution tools; the same workflow augmented with expert-inspired viewer inspection and measurement tools exposed through the Model Context Protocol (MCP); and visual question answering from prescribed rendered 2D images using an agent harness. All settings use the same task-specific deterministic final-answer scoring. The inspection environment supports view changes, target isolation, and slice inspection. In this main comparison, the best mean answer score is 0.53 out of 1. Mean scores in the native-artifact workflow without additional MCP tools exceed those in the rendered-image workflow for every model, by 17.2 percentage points on average.

Towards Automatic Heart Murmur Characterization from Multi-spot Phonocardiograms

arXiv:2611.03654v1 Announce Type: new Abstract: Cardiac auscultation traditionally detects the presence of a heart murmur, but clinicians further characterize it by timing, shape, pitch, quality, and grade. Most automatic phonocardiogram analysis systems stop at binary detection and do not estimate this richer description. In this work, we formulate automatic murmur characterization as five patient-level classification tasks and compare three multi-spot strategies on recordings from the aortic, pulmonary, mitral, and tricuspid auscultation locations. First, classical and deep-learning classifiers are trained independently at each location, and predictions are combined via a maximum-severity late-fusion rule. Second, a synchronous multi-input CNN jointly processes one representative segment per location for a single task. Third, a unified multi-input, multi-output CNN predicts all five attributes from one shared multi-spot representation. Using 735 patients from the CirCor DigiScope dataset with complete four-spot recordings, the best late-fusion configurations reach an unweighted mean sensitivity between 85.56% and 93.81% across the five tasks, with class-specific recalls between 80.00% and 100.00% for every relevant category. The multi-input CNN trails late fusion by 7-16 points depending on the task, while the multi-output model reaches values between 72.59% and 79.40%, estimating all five attributes from one shared representation. We further show that naively balancing training data by adding all minority-class segments degrades patient-level performance under the maximum-severity rule, since it introduces non-representative, noisy segments not filtered by the clustering-based segment selection used for evaluation. These results indicate multi-spot murmur characterization is feasible with both fusion-based and jointly learned architectures, outlining a path toward automatic, structured murmur reports complementing binary screening.