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esm1b_t33_650M_UR50S

facebook · esm1b_t33_650M_UR50S

ESM-1b (paper, repository) is a transformer protein language model, trained on protein sequence data without label supervision. The model is pretrained on Uniref50 with an unsupervised masked language modeling (MLM) objective, meaning the model is trained to predict amino acids from the surrounding sequence context. This pretraining objective allows ESM-1b to learn generally useful features which can be transferred to downstream prediction tasks. ESM-1b has been evaluated on a variety of tasks related to protein structure and function, including remote homology detection, secondary structure prediction, contact prediction, and prediction of the effects of mutations on function, producing state-of-the-art results. **Important note**: ESM-2 is now available in a range of checkpoint sizes. For most tasks, ESM-2 performance will be superior to ESM-1 and ESM-1b, and so we recommend using it instead unless your goal is explicitly to compare against ESM-1b. The ESM-2 checkpoint closest in size to ESM-1b is esm2_t33_650M_UR50D. The ESM-1b model is based on the RoBERTa architecture and training procedure, using the Uniref50 2018_03 database of protein sequences. Note that the pretraining is on the raw protein sequences only. The training is purely unsupervised -- during training no labels are given related to structure or function.

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컨텍스트 창미공개
입력 → 출력텍스트 → 텍스트
모델 웨이트미확인
정보 업데이트2026/10/30 01:28:54
OVERVIEW

모델 소개

ESM-1b (paper, repository) is a transformer protein language model, trained on protein sequence data without label supervision. The model is pretrained on Uniref50 with an unsupervised masked language modeling (MLM) objective, meaning the model is trained to predict amino acids from the surrounding sequence context. This pretraining objective allows ESM-1b to learn generally useful features which can be transferred to downstream prediction tasks. ESM-1b has been evaluated on a variety of tasks related to protein structure and function, including remote homology detection, secondary structure prediction, contact prediction, and prediction of the effects of mutations on function, producing state-of-the-art results. **Important note**: ESM-2 is now available in a range of checkpoint sizes. For most tasks, ESM-2 performance will be superior to ESM-1 and ESM-1b, and so we recommend using it instead unless your goal is explicitly to compare against ESM-1b. The ESM-2 checkpoint closest in size to ESM-1b is esm2_t33_650M_UR50D. The ESM-1b model is based on the RoBERTa architecture and training procedure, using the Uniref50 2018_03 database of protein sequences. Note that the pretraining is on the raw protein sequences only. The training is purely unsupervised -- during training no labels are given related to structure or function.

주요 특징

特点摘要待依据来源补齐,不凭模型名称推断能力。

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공개 평가 및 실행 설정

暂无已采集的可核验公开评分。模型未上榜不代表能力较低。

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출처 및 추적 기록

许可证:mit。模型介绍与第三方评测均以原来源的具体版本和方法为准。